Django + Postgres on the backend plus a frontend of HTMX + alpine.js for a light touch of interactivity where needed is a killer combination. Claude is very good at it, and with the right instructions actually keeps things concise and modular without spilling into spaghettification. I would recommend this as a first option to anyone looking to spin up a new web stack if you’re not absolutely sure you need the heavyweight of React.
I've built a couple non-trivial, cross-platform apps with alpine.js and htmx with tauri as the sole backend with ipc. Claude is very good at full-stack with the tauri mcp driving harder e2e tests that leverage platform APIs.
